A team of researchers fromSungkyunkwan Universityhave used a commercially available inkjet printhead to fabricate wearable medical biosensors for personalized health monitoring. Using a soft, flexible silicone elastomer with a sugar scaffold, the team was able to print high-resolution features in a lightweight, electrically conductive package. The moldable biosensors are being used to detect actively changing body strain signals as well as passively changing electromyography (EMG), electrodermal activity (EDA), and electroencephalogram (EEG) signals.
个性化的医疗服务
个性化医疗服务的3D打印将始终需要高水平的可定制性。对于药物输送设备，例如片剂，剂量将是定制的，而对于手术前的解剖模型，患者的轮廓将是它们独特的。同样，3D打印的可穿戴生物传感器必须符合患者身体的形状并留在那里。为此，它们必须灵活，轻巧且无毒。为了检测皮肤下电信号的变化，它们还必须高度敏感，当然也必须进行导电。
3D打印可穿戴生物传感器
With the extensive set of requirements in mind, the Korean researchers first acquired some 3D anatomical body scans from volunteer patients. These scans went on to be used as a point of reference to model the personalized wearable biosensors. The team 3D printed a porous sugar scaffold for each of the wearable devices and injected the pores with a silicone elastomer filler (among other additives) to give the sensors their elasticity. Once the sugar scaffolds dissolved, all that was left was a low density, highly flexiblemicrocellular network‐type interconnected conductive material.
A number of experiments were conducted to test the functionality of the newly printed biosensors including a comprehensive sleep study measuring brainwaves and a treadmill study measuring neuron activity in muscle tissue. The researchers concluded that the patient-specific 3D printed sensors were highly sensitive to minute electrical signal changes under the skin, in the muscles, and in the brains of the volunteers. They were able to monitor the rapidly changing human body signals in real time to a high degree of precision, adding another application to 3D printing’s growing list of uses. The researchers intend to develop the technology further to encompass a number of other personalized point-of-care diagnostics.
该研究的更多细节可以在标题为“”的论文中找到3D‐Printed Sugar Scaffold for High‐Precision and Highly Sensitive Active and Passive Wearable Sensors’. It is co-authored by Dong Hae Ho,Panuk Hong,Joong Tark Han, Sang‐Youn Kim,S. Joon Kwon，以及钟cho。
The 3D printing of sensors is one of those novel applications that is quickly gaining traction from researchers and companies alike. Earlier this month,REHAU，领先的聚合物制造商，成功3D printed a touch sensor using Nano Dimension’s AM electronics technology. By integrating an electronic circuit, REHAU was able to functionalize one of its premium polymer materials as part of its ‘Electronics into Polymers’ program. Elsewhere, at theUniversity of Lincoln, researchers have原型a3D打印，传感器操作的假肢为幼儿设计。
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特色图显示了3D打印可穿戴传感器的过程。通过Skku的图像。
