3D printing may be used as powerful tool for neural tissue engineering according to new research.
退化性疾病或创伤是神经损害的主要原因。专家认为仅在美国there are approximately 2.8 million cases of traumatic brain injury every year。Neural regeneration, the神经组织，细胞或细胞产物的再生或修复可以帮助修复这种损害。但是，修复大面积的破坏是一项艰巨的任务。
Scientists from the George Washington University have found that a 3D printed neural scaffold together with LLLT will, “generate a new strategy to repair neural degeneration.透明
研究人员修改了SLA 3D打印机
根据这项研究，3D打印是组织再生的有吸引力的选择，因为
Its capability of spatially controlling the placement of functional components to generate a complex 3D scaffold. This process offers a patient-specific design feasibility, enabling researchers to tailor 3D printed implants to specific injuries, further increasing probability of complete recovery.
此外，与传统的脚手架制造方法相比，3D生物打印是一种更有利的方法，因为它允许“”通过调整可打印材料的计算机辅助设计和配方来产生受控的孔隙率和机械性能。透明
To prepare the neural scaffolds the researchers developed a stereolithography-based 3D printer based on the Printrbot platform. One vital modification to the printer was the addition of a 110 µm fiber optic coupling with a solid-state UV laser source (355 nm). Using the customised 3D printer a “天然凝胶和合成踏板的组合透明was printed in the desired shape.
Enhanced cell proliferation after low-level light stimulation
将3D打印的神经支架与神经干细胞（NSC）接种，并每隔一天暴露于低水平的光线中，持续15秒钟。然后测量细胞的增殖，研究人员在针对对照组进行测量时发现大幅增加。
When compared with the control test which lacks the LLLT treatment, the cells stimulated with laser for 15 s exhibited the highest cell proliferation rate at 24 h of culture after stimulation, namely, a 44.4% higher cell proliferation.
研究的成功可以为开发新一代神经疗法的新方法铺平”，根据研究团队的说法。
Illustrating the multi-disciplinary approach that 3D printing research involves, the research was a collaborative effort by the several departments at the George Washington University. Specifically the Departments of Mechanical and Aerospace Engineering, Electrical and Computer Engineering, Biomedical Engineering and the Department of Medicine.
这项研究是由Wei Zhu，Jonathan K. George，Volker J. Sorger和Lijie Grace Zhang进行的。“3D printing scaffold coupled with low level light therapy for neural tissue regeneration透明is published in theOfficial Journal of the International Society for Biofabrication.
Recently, 3D Printing Industry reported on how 3D Systems are working on联合疗法的生物打印项目如何Japanese researchers are 3D printing liver cells。
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