Materials

Jellatechreaches new milestone in collagen bioink development

生物材料开发人员Jellatechhas announced a new milestone in the development of its 3D printable cell-based collagen bioink.

经过两年的发展,该公司成功地设计了由自己专有的细胞系制成的全长,三螺旋和功能性的胶原蛋白。

Jellatech首席执行官Stephanie Michelsen说:“这对我们来说是一个重要的里程碑,我为我们已经在这里而感到自豪和兴奋。”“能够用肉眼看到我们干净的基于细胞的胶原蛋白 - 它带来了快乐的眼泪。”

Jellatech's pure, white collagen in powder form. Photo via Jellatech.
Jellatech’s pure, white collagen in powder form. Photo via Jellatech.

3D printing with collagen

Collagen is one of the most unique and abundant proteins in mammals found in connective tissue, skin, tendon, bone, and cartilage. It provides structural support to tissues and plays an important role in cellular processes like tissue repair, immune response, and cell migration.

胶原蛋白的财产已导致它在许多行业中广泛使用,例如生物医学,健康,个人护理和美容,材料以及食品和饮料领域。但是,由于仅在动物和植物中发现蛋白质,许多公司正在寻找其他新颖和可持续的来源。

In regards to 3D printing applications, so far collagen-based bioinks have been engineered with thepotential for tissue regeneration, 去创造breast implants for cancer survivors和生产artificial cartilage for joint reconstruction, 除其他事项外。

Cell-based collagen bioinks have also been instrumental in the3D打印的Alt-Meat的增长市场,harnessed by the likes of MeaTech,重新定义肉, 和别的

Jellatech认为,随着其新的生物互开发,它现在可以对可持续细胞的胶原蛋白生产有答案,它说这可能会导致未来进一步的新颖应用。

Jellatech团队。通过Jellatech的照片。
Jellatech团队。通过Jellatech的照片。

Jellatech的胶原蛋白生物INK

根据Jellatech的说法,基于细胞的胶原蛋白比植物胶原蛋白具有许多优势。例如,由于无法提供与动物衍生的胶原蛋白相同的功能,因此对植物性胶原蛋白生物学的应用受到限制。

“Collagen formation is a complex process that requires specialized machinery found only in mammalian cells,” said Christopher Gilchrist, Senior Scientist at Jellatech. “We’re working to harness the innate ability of these cells to produce collagen that is bio-identical to native collagen and do it in a sustainable and animal-free way.”

该公司的胶原蛋白生产过程完全避免了动物的屠杀,从而在其实验室的生物反应器中培养了动物细胞系的小皮肤样品。通过一系列工艺提取,纯化和过滤胶原蛋白,形成与从动物中提取的胶原蛋白生物认同的胶原蛋白生物互联。

Jellatechrefers to its process as “100% guilt-free” due to bypassing animal slaughter completely, and sees it as a sustainable alternative source of collagen.

Jellatech科学负责人Rob Schutte补充说:“我们很高兴看到我们的细胞来源的胶原蛋白似乎是源自动物的胶原蛋白的生物。”“因此,从生物医学到化妆品再到食品和饮料,我们都有广泛的激动人心的应用。”

Convinced her firm’s cell-based technology is a step ahead of other collagen production technologies currently contributing to the global $8.4 billion market, Michelsen added: “It is becoming more and more evident that we need to change many of our existing practices and the way that we sustain our planet.

“这一成就只是表明我们有办法,现在我们已经奠定了阶梯式石头,以实现蛋白质生产的可持续未来。”

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特色图片显示Jellatech’s pure, white collagen in powder form. Photo via Jellatech.