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尺寸INXraises $12M in funding: aims to boost the commercialization of a new generation of regenerative therapeutics

生物材料平台公司尺寸INXhas announced that it has closed a $12M Series A Round.

Prime Movers Lab(PML) led the round, with cooperation from returning investorsKDT冒险and革命崛起的休息种子基金(ROTR).Solas BioVentures,Portal Innovation Ventures, andAlumni Ventures是本轮新投资者之一。这些资金将用于加速功能器官再生治疗疗法的开发并扩大公司的制造能力。该资金将用于在不久的将来协助该公司的第一个产品CMFLEX的商业发布。

尺寸INXalso revealed that CMFlex, the first 3D printed restorative bone graft product approved by the FDA, has obtained 510(k) clearance from the US Food and Drug Administration (FDA). CMFlex, a ready-to-use versatile ceramic for oral and maxillo-facial indications, enhances clinician workflow and decreases surgical case time whilst also restoring healthy bone.

Prime Movers Lab Venture合作伙伴Amy Kruse博士说:“ Dimension INX代表了我们认为将改变其行业并重塑其物理世界的突破科学类型。”谁将加入公司董事会。“我们很高兴能在下一阶段的增长和开发阶段,并将其变革性产品推向市场时,我们很高兴支持Dimension Inx。”

“FDA clearance is a major milestone for our platform, and validates the work we’ve put into developing our product over the past two years,” said CEO of Dimension Inx, Caralynn Nowinski Collens, M.D. “CMFlex is a product that represents our unique approach to restoring functionality in the body: it’s a dynamic collaboration between biology, material composition, microstructure, and macro architecture. We’re excited by the interest we’ve already received from surgeons who recognize the importance of a ready-to-use solution that is easy to handle and accelerates healing to improve patient outcomes.”

源自卵巢组织的一小部分组织纸的代表性例子,突出了其独特的微孔和质地。图像通过Dimension INX。
源自卵巢组织的一小部分组织纸的代表性例子,突出了其独特的微孔和质地。图像通过Dimension INX。

Dimension INX的工业3D打印组合

以前是一个团队卡内基·梅隆大学()和康涅狄格大学(UConn) researchers 3D printed novel calcium phosphate graphene (CaPG) scaffolds that could be utilized for bone restoration applications in the future.Dimension INX的直接墨水写作(DIW)3D打印方法was used by the team to print porous concepts of its CaPG material with a large weight fraction to allow a “significantly high” graphenic content inside the ink (around 90%). This allowed cellular access to the osteoconductive backbone and the sustained release of phosphate and calcium ions, indicating that the operational graphenic content, instead of the bioinert binder, dominated the host’s response to the matrix.

Collens博士补充说:“我们为催化步骤功能的变化而感到自豪,以释放再生疗法治疗复杂疾病的全部潜力,我们很高兴能在投资者的支持下这样做。”“我们的方法一直集中在整个组织微环境上。如果我们提供合适的蓝图,我们将有可能招募人体的自然优势,并加速修复,再生,并最终恢复关键身体功能。”

此外,US Department of Defense(国防部)授予尺寸INX $ 240,000的资金to build a regenerative medical system capable of restoring tracheal injuries. The project used the company’s patented biomaterials platform to produce implantable parts that mimic the tracheal microenvironment and merge them with a novel hydrogel to assist in remodeling into typically functional tracheal tissue.

Dimension INX已筹集了超过300万美元,以资助其3D生物打印技术的发展。图像通过Dimension INX。
Dimension INX已筹集了超过300万美元,以资助其3D生物打印技术的发展。图像通过Dimension INX。

Series funding rounds that were carried out in the additive manufacturing sector

以前,总部位于旧金山的按需制造服务提供商Fictivraised $100 million inSeries E funding。这一轮资金将该公司的总资本筹集到约1.92亿美元。激活资本led Fictiv’s Series E round, with participation from established institutional investors加速, 比尔盖茨,G2风险合作伙伴, and标准投资Angeleno Group,Cross Creek, and西方集团加入了新投资者。

Elsewhere, Swiss carbon fiber 3D printing specialist9T实验室raised $17 million inA系列资金,它用来将其红色系列添加剂融合解决方案平台进行商业化。该平台结合了3D打印和压缩成型,旨在创建高级碳纤维增强的热塑性复合零件的数量,每年从100到100,000多个零件不等。在工业3D打印机制造商的支持下Stratasys公司除其他主要投资者外,9T实验室还试图将平台全面商业化,以生产用于航空航天,汽车,医疗,工业和消费品行业的最终用途应用程序的组件。

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Feature image shows a representative example of a small sheet of Tissue PaperTM derived from ovarian tissue, highlighting its unique micro- and nano-porosity and texture. Image via Dimension Inx.

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