Medical & Dental

巴斯夫和CTI生物技术开发具有3D生物打印的功能性皮肤腺模型

巴斯夫Care Creations, a department of chemical company巴斯夫,已经证明了与CTI Biotech进入人皮肤腺的3D组织模型。

这些结果在NYSCC化妆品大会上宣布,证明了皮脂的成功前体(在人体之外)生产和主动成分调节,这是皮脂腺(在大多数皮肤细胞中)分泌的蜡状,保护性的。

3D modeling of sebaceous glands

The research involved the use of 3D human sebaceous gland modeling by CTI Biotech. This regenerative medicine R&D company specialises in studies of skin cosmetics, stem-cells and cancer, having recently installed aCELLINK BIO X 3D printerto develop treatments for the latter.

The company’s 3D human sebaceous gland technology, capable of创建和发展人类皮脂细胞模型,与定制和人为分层的皮肤衍生细胞模型一起生物打印。

总部位于里昂的CTI Biotech于2016年开始内部生物报纸,该生物构成了其3D组织工程能力以进行皮肤研究。

“与当前的体外方法相比,CTI Biotech开发的3D模型允许分析[]与人类生理学和皮脂腺代谢有更多联系,”

巴斯夫项目负责人Sabine Pain博士说:“我们对皮脂腺代谢的理解为开发和测试用于皮肤护理应用的先进化妆品生物活性的基础,尤其是针对油性皮肤的护肤产品。”

A hair follicle and sebaceous gland model. Photo via Wikimedia.
A hair follicle and sebaceous gland model. Photo via Wikimedia.

Combining tissue engineering with dermatology in 3D bioprinting

CTI Biotech首席执行官Nico Forraz博士认为,在NYSCC化妆品大会上宣布的研究是验证“针对人类皮肤护理研究的强大技术”的关键。

现在,这些发现将用于研究皮脂腺在皮肤疾病中的作用。CTI Biotech正在开发一个3D生物生产工厂,能够将皮脂腺微晶状体排列为皮肤病学模型。

“Because of their experience and expertise in developing solutions for the dermo-cosmetics market, BASF understands the benefits of collaborating with tissue engineering experts,” added Professor Colin McGuckin, Chief Scientific Officer and President of CTI Biotech. “The next evolution of the sebaceous gland model will be based on a 3D bioprinting technology that allows us to fully reproduce micro-glands into a full thickness skin model, in vitro.”

巴斯夫签署了bioprinting deal with French company Poietislast year, which would see joint development of BASF’s “mimeskin” synthetic skin for testing cosmetics.

Colin McGlucklin教授在CTI Biotech的生物打印机。通过CTI生物技术照片。
Colin McGluckin教授与CTI Biotech的生物生产商。通过CTI生物技术照片。

Nominations for the second annual 3D Printing Industry Awards are now open.立即进行选择。

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特征图显示了由CTI Biotech制作的皮脂细胞模型。通过CTI生物技术照片。