Finland-based bioprinting firmbrinterhas launched what it claims is the world’s first multi-material, multi-fluidic bioprinting printhead.
Designed for use with the firm’s own 3D bioprinters, the数字多氟打印工具头is currently undergoing pilot testing with a limited number of customers. Aimed at research institutions and pharmaceutical companies, the device is defined by its extensive material capabilities and hopes to enable higher-precision tissue engineering and regenerative medicine applications, including tissue damage repair, biological function replacements, and localized disease treatments.
Brinter首席执行官Tomi Kalpio说：“实现这一世界优先的关键是我们团队成员的积累经历，利用我们专有的硬件架构，软件和流动性自动化系统知识来使复杂的流体电路变得复杂，它们的死亡接近于零。量以节省资源并避免与其他材料交叉污染。”
3D生物打印与Brinter
Established in 2020 as a spin-out from 3D printing service bureau3Dtech Ltd，Brinter专门为药品，生物技术，研究和化妆品领域的客户提供3D生物打印机，油墨和相关硬件。该公司目前在美国，英国和德国等十个国家 /地区拥有客户，包括Nanoform,Johannes Gutenberg University of Mainz,University of Oulu，和University of Helsinki。
去年，Brinter成为头条新闻120万欧元的种子资金扩大其日常运营并将其生物打印发行带到美国和欧洲医疗市场。
The company’s debut bioprinter is its flagshipBrinter One这是一种基于多物质沉积的机器，可与僵硬和软细胞的水凝胶一起使用。最近11月，Brinter也推出了entry-level model called the Brinter Core。旨在使生物打印尽可能易于使用，核心大约是其前身的大小和成本的一半。
March 2022 was also an active month for Brinter, when it partnered with extrusion technology developerPuredyne启动它new Visco Bio printhead。不久之后，该公司与坦佩雷大学的Kellomäki Lab Biomaterials and Tissue Engineering Group todevelop new bioinks for use with the technology。
第一个多材料的多流体打印头
新的多物质打印头的最值得注意的功能是其充足的可调性。可以通过不同的温度控制和成像选项来修改硬件，以使其与多种材料类型兼容。根据Brinter的说法，打印头能够在单个构建中打印多达4,096种不同的材料组合。
没有这种可调节性，每种类型的印刷材料都可能需要新的打印头，这在处理颗粒，糊状和液体时非常不便。材料能力列表还包括带有活细胞的水凝胶，生物托架，注入金属的粘合剂，甚至是聚合物。
Kalpio states that the printhead serves to bridge the gap between the micro/nano/pico/femto fluidic environments and the bioprinting environment, granting users the utmost level of deposition precision.
As such, the number of potential Brinter use cases is significantly expanded. The company claims customers will be able to generate gradients across their bioprinted structures, program the cells in the droplets to make personalized drugs, and even functionalize printed materials to perhaps one day target cancer cells or heal and regenerate tissues.
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特色图显示了Brinter的生物打印系统，模块和墨水的投资组合，用于医疗，研究和化妆品客户。通过Brinter照片。
