Research

Q&A: RMIT’s Dr. Kate Fox adding nanodiamonds to 3D printed implants

3D印刷行业最近介绍了研究人员的一项研究RMIT University, Australia, proving thatdiamond-coated titanium implantscould improve biocompatibility within the body.

凯特·福克斯博士led this research titled “Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications,” which is published inACS应用材料和界面.

我是RMIT电气和生物医学工程学院的高级讲师,我采访了Fox博士,以了解有关Nanodiamond Technology的潜力以及她团队研究的下一步的更多信息。

A hollow, 3D printed titanium cube. Heated for diamond coating. Photo via RMIT University
A hollow, 3D printed titanium cube heated for diamond coating acts as a demonstration in Dr. Fox’s research. Photo via RMIT University

3D打印行业:纳米木木涂料是否独有化合物制造的医疗植入物?

凯特·福克斯(Kate Fox)博士,RMIT大学:The diamond technology can be applied to substractively manufactured titanium if one so chooses. The 3D printed titanium implants however offer a lot more flexibility towards patient specific implants as the implant can be designed to fit the individual’s needs.

This [3D printed] titanium however, does not interact with the body as well as we would have liked. As a result, the study was to coat the 3D printed titanium with diamond to improve the tissue interface. Now that we can, it opens up the opportunity for customized diamond implants.

3D Printing Industry: One of the main advantages of 3D printing implants is adding porosity and other geometries to promote bone in-growth. Is this coating method successful at reaching into pores/scaffolds?

凯特·福克斯(Kate Fox)博士,RMIT大学:The coating method is able to coat in a line of sight. The diamond does penetrate down the pores but it is necessary to turn the scaffolds in the reactor.

基本上,如果化学蒸气沉积(CVD)腔室内的等离子体看不到表面,则表面没有覆盖。这意味着孔的底部被涂覆,但涂层限制为侧壁1-2mm。

图像显示了3D印刷和钻石涂层钛植入物的表面粗糙度。图片通过RMIT大学
图像显示了3D印刷和钻石涂层钛植入物的表面粗糙度。图片通过RMIT大学

3D Printing Industry: Are there any specific applications that you believe diamond coated implants would work better than uncoated implants? i.e. Are there areas that are particularly challenging to biocompatibility?

凯特·福克斯(Kate Fox)博士,RMIT大学:生物相容性对于所有植入物都是必不可少的,但是对于这些钻石植入物,我们专注于将直接与硬组织接触的植入物。目前,颅面,骨螺钉和骨板在我们的视线中。

3D打印行业:现在您证明了钻石涂料的可行性,您的研究下一步是什么?

凯特·福克斯(Kate Fox)博士,RMIT大学:The next step is to undergo a more comprehensive pre-clinical trial to truly understand the interaction of the implants with bone as well as scale up the technology to larger, more complex implants. And of course, find interested industry partners to share the journey with.

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特色图片显示了一个空心的3D印刷钛合金物,加热钻石涂层。通过RMIT大学的照片