生物技术启动Nuclerahas attracted a further $15.5 million in Series B funding, taking its total raised in the round up to $58 million.
很像最初筹集了4250万美元earlier this year, Nuclera plans to use this additional capital to fund the continued development of its“ eprotein” 3D生物运输工组。It’s thought that once ready, the technology, which enables scientists to more rapidly create the samples needed to study protein-to-protein interactions (PPIs), could help accelerate and democratize the drug discovery process.
“We’re delighted by the continued support of our existing investors and to have the opportunity to bring on several new strategic partners with our recent Series B raise,” said Nuclera CEO and Co-founder Michael Chen. “With their support, we are quickly scaling all functions from R&D through to our commercial team.”
“我很高兴推动我们使蛋白质可访问的使命，并继续我们的旅程，将改变游戏规则的技术传播到市场。”
Nuclera的蛋白质3D生物打印过程
由三位科学家创立剑桥大学in 2013, Nuclera is a biotechnology specialist that’s dedicated to driving the accessibility of cell-based experimentation. Primarily, the firm has sought to achieve this via the development of the eProtein, a bioprinter designed to help scientists accelerate the rate at which they identify proteins, in mammalian, plant, and bacterial cells.
The system is powered by Nuclera’s ‘eDrop’ digital microfluidic technology, a lab-on-a-chip process, in which the TFT electronics used to create consumer displays are deployed to screen DNA droplets for protein expression instead.
Based on this data, the machine can then use software-controlled electronic signals to move, mix and split such droplets, in a way that enables the creation of purified nanoliter-scale proteins. In doing so, Nuclera says its technology accelerates what is often a “time-consuming and complex process” that can take months or even years to accomplish, into one that’s achievable within just 24 hours.
The company has also developed its own ‘eDNA synthesis ink.’ This enzyme effectively turns monomer building blocks into DNA strands, theoretically enabling eProtein users to rapidly create a desired sequence for testing, on-demand at their desk. According to Nuclera, the biomaterial therefore connects the workflows behind DNA, RNA and protein synthesis, which “are currently fragmented” and slow.
资助Eprotein的市场首次亮相
Nuclera最新的1550万美元投资provided by biotech entrepreneur Jonathan Milner, as well as VC firmVerve Ventures。The investors’ move sees them join the firm’s growing list of backers, which includes the likes ofM&G，，，，Amadeus Capital Partners，，，，and RT Partners, and takes its total raised to $83.3 million.
Using its newly-raised funding, Nuclera says that it plans to “further its mission of making biology accessible.” Specifically, the company intends to achieve this by pouring more resources into the eProtein’s launch, something it’s preparing for by working with key customers to gather intelligence, and engaging in alpha testing.
为了加速其商业前战略，Nuclera还宣布了计划在其关键职能中雇用新人员。一旦准备就绪，该公司认为其系统将“允许研究人员通过提供按需，台式机访问3D Bioprinting来加速发现和治疗”，Milner表示可能是革命性的。
米尔纳解释说：“能够在24小时内筛选多种蛋白质表达概况和打印纯化的蛋白质，将彻底改变实验室工作流程，并在学术界和药物发现时间表上发表的时间产生明显的影响。”“一次筛选单个蛋白质表达剖面的日子正结束这项技术。”
3D Biopinting的投资者上诉
While 3D bioprinting largely remains at the lab-testing stage, its potential as a means of producing transplantable tissues continues to attract significant investor interest. In May 2022, for example,Regemat 3D筹集了超过500,000欧元在股票众筹中，它用来提高其专有生物打印技术的发展。
Earlier this year,Inventia Life Science raised $25 million同样，为其提供加快其推出所需的现金RASTRUM3D bioprinter. The firm sees particular potential for its system in the US biotech sector, where it believes it can address a tissue R&D and drug discovery market worth an estimated $40 billion.
Biolife4d，，，，meanwhile, has sought to raise funding in a different way, by launching a$17.5 million IPO in the US。Using any cash raised, the firm plans to expand its R&D operations, as a means of commercializing the technology behind its mini 3D bioprinted heart, which could be used as a basis for creating human tissue grafts.
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特色图像显示了使用Nuclera系统的工程师。通过Nuclera照片。
